Blockchain and RISC-V

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RISC-V is a new free and open instruction set architecture (ISA) developed at UC Berkeley, initially designed for research and education, but is now increasingly being used for commercial designs.

RISC-V is currently being used in and developed for a variety of products but mostly hardware and relatively new in the blockchain space.
The most well-known blockchain Virtual Machine, the Ethereum Virtual Machine is moving to WebAssembly (eWASM).
Nervos Common Knowledge Base (CKB), an open-source public blockchain (Github: nervosnetwork), uses RISC-V in building its Virtual Machine.